LIU Ying, ZHANG Wei-zhong, YIN Yan-fei, ZHANG Zhi-liang, ZHANG De-fa. 2-Phase Hemodynamic Analysis Under Bidirectional Fluid-Structure Interaction in the Left Coronary Artery With Stenosis[J]. Applied Mathematics and Mechanics, 2016, 37(5): 501-509. doi: 10.3879/j.issn.1000-0887.2016.05.006
Citation: LIU Ying, ZHANG Wei-zhong, YIN Yan-fei, ZHANG Zhi-liang, ZHANG De-fa. 2-Phase Hemodynamic Analysis Under Bidirectional Fluid-Structure Interaction in the Left Coronary Artery With Stenosis[J]. Applied Mathematics and Mechanics, 2016, 37(5): 501-509. doi: 10.3879/j.issn.1000-0887.2016.05.006

2-Phase Hemodynamic Analysis Under Bidirectional Fluid-Structure Interaction in the Left Coronary Artery With Stenosis

doi: 10.3879/j.issn.1000-0887.2016.05.006
Funds:  The National Natural Science Foundation of China(51165031)
  • Received Date: 2015-09-09
  • Rev Recd Date: 2016-01-26
  • Publish Date: 2016-05-15
  • Treated as a 2-phase flow, the blood flow in the left coronary artery with stenosis was transiently simulated with the method of computational fluid mechanics, under the bidirectional fluid-structure interaction between the blood flow and the vascular wall. The blood flow distribution characteristics in the left coronary artery was analyzed at typical moments within a cardiac cycle, and the effects of the 2-phase blood model plus the fluid-structure interaction on the hemodynamics were studied in comparison with those of the Newtonian blood model and the 2-phase blood model. The results show that, in the proximal outside of the obtuse marginal and the distal part of the left circumflex branch there appear low-speed eddy zones where both the wall shear stress and the red blood cells’ volume fraction are relatively small, resulting in a suitable physical environment for the formation and development of atherosclerosis. The wall displacement at the left coronary artery bifurcation is rather large, making a possible cause for the disfunctions of the vascular wall intima, which also prompts the formation of the atherosclerotic plaques. The comparison between different blood models shows, the flow characteristics of red blood cells have considerable influences on the hemodynamics of blood flow velocity and wall shear stress, and the bidirectional fluid-structure interaction model is more consistent with the true situation of the blood flow.
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