New Approach to Minimize Dispersion Induced by Turn in the Capillary Electrophoresis Channel Flows

LI Zhi-hua; LIN Jian-zhong; NIE De-ming

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Article Navigation > Applied Mathematics and Mechanics > 2005 > 26(6): 631-636

LI Zhi-hua, LIN Jian-zhong, NIE De-ming. New Approach to Minimize Dispersion Induced by Turn in the Capillary Electrophoresis Channel Flows[J]. Applied Mathematics and Mechanics, 2005, 26(6): 631-636.

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New Approach to Minimize Dispersion Induced by Turn in the Capillary Electrophoresis Channel Flows

1.
Department of Mechanics, State Key Laboratory of Fluid Power Transmission and Control, Zhejiang University, Hangzhou 310027, P. R. China;
Zhejiang University of Science and Technology, Hangzhou 310012, P. R. China

Received Date: 2003-06-16
Rev Recd Date: 2005-01-25
Publish Date: 2005-06-15

Abstract

Abstract

The mechanism of dispersion induced by turn in the capillary electrophoresis channel flows was analyzed firstly.Then the mathematical model of electroosmotic flow is built,and the dispersion of the flow,with different distribution of charge at inner and outer wall in the turns,was simulated numerically using the finite differential method.A new approach of altering the distribution of charge at inner and outer wall in the turns was presented,based on the computational results,to minimize the dispersion induced by turn.Meanwhile,an optimization algorithm to analyze the numerical results and determine the optimal distribution of charge in the turns was also developed.It is found that the dispersion induced by turn in the capillary electrophoresis channel flows could be significantly suppressed by this approach.
- micro-flow,
- electrophoresis,
- electroosmotic,
- dispersion,
- turn

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References(8)

References

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